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In response to the COVID-19 pandemic, JoyRx Music (flagship program of Children’s Cancer Association) developed SINGO, a fun and accessible virtual music activity for hospitalized children and teens. Due to restrictions brought on by the pandemic, our hospital partners faced reduced capacity and resources, limiting the activities available to pediatric patients during their hospital stay. To fill this critical enrichment need, JoyRx Music developed a musical activity that is interactive, inclusive, accessible, and easy for hospitals to host. Designed to improve a patient’s social-emotional well-being and combat isolation, SINGO, a musical version of BINGO, is a fun and interactive concert performed by a trained JoyRx Music Specialist. Patients enjoy a live concert broadcast via Zoom through the hospital’s CCTV network, while checking off boxes on their SINGO card. SINGO concerts are designed so that every participant wins the game, and JoyRx prizes are handed out by hospital staff at the end of the concert. A fun and interactive music activity with great impact!